IMIS - Marine Onderzoeksgroepen | Compendium Kust en Zee

IMIS - Marine Onderzoeksgroepen

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Groupe de Recherche en Spectrométrie de Masse (Umons)
http://portail.umons.ac.be/FR/universite/facultes/fs/services/institut_chimie/chimie_organique/recherche/groupe_recherche_spectrometrie_de_masse/Pages/GroupedeRechercheenSpectrom%c3%a9triedeMasse.aspx
De onderzoeksactiviteiten op het gebied van massaspectrometrie gingen in Bergen van start in het midden van de jaren 1960, toen het laboratorium voor Organische Chemie van de faculteit Wetenschappen de eerste massaspectrometer verwierf. Nu bestudeert het laboratoire de Synthèse et Spectrométrie de Masse Organiques (S2MOs) de volgende onderzoeksthema's:
  • chemie van natuurlijke moleculen zoals saponinen, flavonoïden, lipiden en polysacchariden om (i) de moleculaire diversiteit in levende organismen zoals planten, microalgen of zeedieren vast te stellen en zo hun biologische rol te bepalen; (ii) de structuur van natuurlijke moleculen te wijzigen om hun biologische eigenschappen te versterken; (iii) complexe biologische moleculen te gebruiken om massaspectrometrische technieken te ontwikkelen, met name ionenmobiliteitsspectrometrie;
  • chemie van synthetische macromoleculen zoals biologisch afbreekbare of geconjugeerde polymeren om hoofdzakelijk MS-methoden voor hun structurele karakterisering te optimaliseren of onze partners te helpen hun synthetische ontwikkelingen te valideren;
  • chemie van peptoïden, dat zijn synthetische biomimetische moleculen van peptiden om (i) de relatie primaire structuur/secundaire structuur vast te stellen en (ii) de structurele diversiteit van deze moleculen te gebruiken om chirale selectoren te creëren of systemen die zonne-energie kunnen opslaan (Molecular Solar thermal Energy Storage - MOST);
  • ontwikkeling van massaspectrometriemethoden voor de analyse van oorspronkelijke organische moleculen, met bijzondere aandacht voor ionisatie/desorptie, diverse ionactiveringstechnieken en ionmobiliteitsscheiding.


Overkoepelend instituut: Université de Mons; Faculté des Sciences; Département de Chimie (Umons), meer

Adres:
Place du Parc 20
7000 Mons
België 		 
Type: Wetenschappelijk
    ( 20 peer reviewed ) opsplitsen filter
  • Peer reviewed article Claereboudt, E.J.S.; Claereboudt, M.R.; Savarino, P.; Caulier, G.; Gaumez, L.; Deleu, M.; Gerbaux, P.; Eeckhaut, I. (2023). A distinct saponin profile drives an olfactory-mediated aggregation in the aquacultivated sea cucumber Holothuria scabra. Mar. Drugs 21(3): 184. https://dx.doi.org/10.3390/md21030184, meer
  • Peer reviewed article Lourtie, A.; Eeckhaut, I.; Mallefet, J.; Savarino, P.; Isorez, M.; Mussoi, L.; Bischoff, H.; Delroisse, J.; Hedouin, L.; Gerbaux, P.; Caulier, G. (2023). Species-specific metabolites mediate host selection and larval recruitment of the symbiotic seastar shrimp. NPG Scientific Reports 13(1): 12674. https://dx.doi.org/10.1038/s41598-023-39527-2, meer
  • Peer reviewed article Savarino, P.; Demeyer, M.; Decroo, C.; Colson, E.; Gerbaux, P. (2023). Mass spectrometry analysis of saponins. Mass Spectrometry Reviews 42(3): 954-983. https://dx.doi.org/10.1002/mas.21728, meer
  • Peer reviewed article Caulier, G.; Lourtie, A.; Brasseur, L.; Mallefet, J.; Gerbaux, P.; Flammang, P.; Eeckhaut, I. (2022). Crinoid anthraquinones as kairomones allowing host selection for the symbiotic snapping shrimp Synalpheus stimpsonii. Chemoecology (Print. ed.) 32(3): 95-104. https://dx.doi.org/10.1007/s00049-022-00368-6, meer
  • Peer reviewed article Cauchie, G.; Delfau-Bonnet, G.; Caulier, G.; Hantson, A.-L.; Renault, J.-H.; Gerbaux, P. (2021). Comprehensive lipid profiling of Microchloropsis gaditana by liquid chromatography - (tandem) mass spectrometry: bead milling and extraction solvent effects. Algal Research 58: 102388. https://dx.doi.org/10.1016/j.algal.2021.102388, meer
  • Peer reviewed article Bouanati, T.; Colson, E.; Moins, S.; Cabrera, J.-C.; Eeckhaut, I.; Raquez, J.-M.; Gerbaux, P. (2020). Microwave-assisted depolymerization of carrageenans from Kappaphycus alvarezii and Eucheuma spinosum: controlled and green production of oligosaccharides from the algae biomass. Algal Research 51: 102054. https://hdl.handle.net/10.1016/j.algal.2020.102054, meer
  • Peer reviewed article Delroisse, J.; Van Wayneberghe, K.; Flammang, P.; Gillan, D.; Gerbaux, P.; Opinã, N.; Todinanahary, G.G.B.; Eeckhaut, I. (2020). Epidemiology of a SKin Ulceration Disease (SKUD) in the sea cucumber Holothuria scabra with a review on the SKUDs in Holothuroidea (Echinodermata). NPG Scientific Reports 10(1): 22150. https://dx.doi.org/10.1038/s41598-020-78876-0, meer
  • Peer reviewed article Claereboudt, E.J.S.; Caulier, G.; Decroo, C.; Colson, E.; Gerbaux, P.; Claereboudt, M.R.; Schaller, H.; Flammang, P.; Deleu, M.; Eeckhaut, I. (2019). Triterpenoids in echinoderms: fundamental differences in diversity and biosynthetic pathways. Mar. Drugs 17(6): 352. https://dx.doi.org/10.3390/md17060352, meer
  • Peer reviewed article Brasseur, L.; Demeyer, M.; Decroo, C.; Caulier, G.; Flammang, P.; Gerbaux, P.; Eeckhaut, I. (2018). Identification and quantification of spinochromes in body compartments of Echinometra mathaei's coloured types. Royal Society Open Science 5(8): 15. https://dx.doi.org/10.1098/rsos.171213, meer
  • Peer reviewed article Brasseur, L.; Caulier, G.; Flammang, P.; Gerbaux, P.; Eeckhaut, I. (2018). Mapping of spinochromes in the body of three tropical shallow water sea urchins. Nat. Prod. Commun. 13(12): 1659-1665, meer
  • Peer reviewed article Brasseur, L.; Caulier, G.; Lepoint, G.; Gerbaux, P.; Eeckhaut, I. (2018). Echinometra mathaei and its ectocommensal shrimps: the role of sea urchin spinochrome pigments in the symbiotic association. NPG Scientific Reports 8(1): 17540. https://dx.doi.org/10.1038/s41598-018-36079-8, meer
  • Peer reviewed article Brasseur, L.; Hennebert, E.; Fievez, L.; Caulier, G.; Bureau, F.; Tafforeau, L.; Flammang, P.; Gerbaux, P.; Eeckhaut, I. (2017). The roles of spinochromes in four shallow water tropical sea urchins and their potential as bioactive pharmacological agents. Mar. Drugs 15(6): 179. https://dx.doi.org/10.3390/md15060179, meer
  • Peer reviewed article Decroo, C.; Colson, E.; Demeyer, M.; Lemaur, V.; Caulier, G.; Eeckhaut, I.; Cornil, J.; Flammang, P.; Gerbaux, P. (2017). Tackling saponin diversity in marine animals by mass spectrometry: data acquisition and integration. Anal. Bioanal. Chem. 409(12): 3115-3126. https://dx.doi.org/10.1007/s00216-017-0252-7, meer
  • Peer reviewed article Brasseur, L.; Parmentier, E.; Caulier, G.; Vanderplanck, M.; Michez, D.; Flammang, P.; Gerbaux, P.; Lognay, G.; Eeckhaut, I. (2016). Mechanisms involved in pearlfish resistance to holothuroid toxins. Mar. Biol. (Berl.) 163(6): 129. https://dx.doi.org/10.1007/s00227-016-2901-3, meer
  • Peer reviewed article Caulier, G.; Mezali, K.; Soualili, D.L.; Decroo, C.; Demeyer, M.; Eeckhaut, I.; Gerbaux, P.; Flammang, P. (2016). Chemical characterization of saponins contained in the body wall and the Cuvierian tubules of the sea cucumber Holothuria (Platyperona) sanctori (Delle Chiaje, 1823). Biochem. Syst. Ecol. 68: 119-127. https://dx.doi.org/10.1016/j.bse.2016.06.005, meer
  • Peer reviewed article Demeyer, M.; Wisztorski, M.; Decroo, C.; De Winter, J.; Caulier, G.; Hennebert, E.; Eeckhaut, I.; Fournier, I.; Flammang, P.; Gerbaux, P. (2015). Inter- and intra-organ spatial distributions of sea star saponins by MALDI imaging. Anal. Bioanal. Chem. 407(29): 8813-8824. https://dx.doi.org/10.1007/s00216-015-9044-0, meer
  • Peer reviewed article Eeckhaut, I.; Caulier, G.; Brasseur, L.; Flammang, P.; Gerbaux, P.; Parmentier, E. (2015). Effects of holothuroid ichtyotoxic saponins on the gills of free-living fishes and symbiotic pearlfishes. Biol. Bull. 228(3): 253-265, meer
  • Peer reviewed article Demeyer, M.; De Winter, J.; Caulier, G.; Eeckhaut, I.; Flammang, P.; Gerbaux, P. (2014). Molecular diversity and body distribution of saponins in the sea star Asterias rubens by mass spectrometry. Comp. Biochem. Physiol. (B Biochem. Mol. Biol.) 168: 1-11. dx.doi.org/10.1016/j.cbpb.2013.10.004, meer
  • Peer reviewed article Caulier, G.; Flammang, P.; Gerbaux, P.; Eeckhaut, I. (2013). When a repellent becomes an attractant: harmful saponins are kairomones attracting the symbiotic Harlequin crab. NPG Scientific Reports 3. https://dx.doi.org/10.1038/srep02639, meer
  • Peer reviewed article Coulembier, O.; Moins, S.; De Winter, J.; Gerbaux, P.; Leclère, P.; Lazzaroni, R.; Dubois, P. (2010). From jellyfish macromolecular architectures to nanodoughnut self-assembly. Macromolecules 43(1): 575-579. dx.doi.org/10.1021/ma901938j, meer
  • Caulier, G.; Lourtie, A.; Gerbaux, P.; Claereboudt, J.S.; Flammang, P.; Eeckhaut, I. (2024). Saponins: multitasking chemical signatures in asteroids and holothuroids, in: Mees, J. et al. Book of abstracts – VLIZ Marine Science Day, 6 March 2024, Oostende. VLIZ Special Publication, 91: pp. 57, meer