Involvement of Neb-colloostatin, a collagen-related peptide, in early vitellogenesis of the grey fleshfly
Bylemans, D.; Proost, P.; Samyn, B.; Van Beeumen, J.; Van Damme, J.; De Loof, A. (1995). Involvement of Neb-colloostatin, a collagen-related peptide, in early vitellogenesis of the grey fleshfly. Neth. J. Zool. 45(1-2): 172-174
In: Netherlands Journal of Zoology. E.J. Brill: Leiden. ISSN 0028-2960; e-ISSN 1568-542X, more
During the purification procedure of the first folliculostatin of the grey flesfly Neobellieria bullata, the Trypspin-Modulating Oostatic Factor (Neb-TMOF), a second factor with oostatic activity, was discovered. Here we report the primary structure and effects on oocyte development of the latter factor. The amino acid sequence was determinated as H-SIVPLGLPVPLVPIGPIVVGPR-OH. Becaue of structural sequence similaritieswith parts of several known collagens and because of itsoostatic activity, we named the factor Neb-colloostatin. The synthetic peptide inhibits yolk uptake by prvitellogenic oocytes and might be the factor that determines that per ovariole only one follicle devellops at a time.
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