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Bioactive nitrogenous secondary metabolites from the marine sponge genus Haliclona
Zhu, J.; Liu, Y.; Liu, Z.; Wang, H.; Zhang, H. (2019). Bioactive nitrogenous secondary metabolites from the marine sponge genus Haliclona. Mar. Drugs 17(12): 682. https://dx.doi.org/10.3390/md17120682
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
Peer reviewed article  
Available in  Authors 
Keywords
Author keywords
    marine sponge; symbiotic microbe; secondary metabolite; alkaloid; bioactivity
Authors  Top 
  • Zhu, J.
  • Liu, Y.
  • Liu, Z.
  • Wang, H., more
  • Zhang, H.
Abstract
    Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery.
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